Optimizing Barrier Repair for
Patients with Atopic Dermatitis

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EpiCeram® is a Prescription-Only Controlled-Release Skin-Barrier-Repair Emulsion that Offers Unique, Non-Steroidal Therapy for Patients with Eczema and Atopic Dermatitis


EpiCeram helps repair and heal the skin barrier through a unique mechanism of action not commonly found in other medications. It contains the skin’s natural level of essential lipids: ceramides, cholesterol and free fatty acids, which are reduced in patients with eczema and atopic dermatitis (AD). EpiCeram is steroid-free, fragrance-free, noncomedogenic, paraben-free, and propylene glycol-free.

Available in a 90g tube and 225g airless pump


How EpiCeram Works:
The Skin's Natural Barrier

The outermost layer of the skin is called the stratum corneum, which is made up of cells called corneocytes. The purpose of this important layer is to protect the skin from bacteria or allergens as well as to help the skin retain water and other important substances necessary for skin protection. The corneocytes are embedded and supported by a lipid-rich matrix to help keep the normal function of this important skin barrier. The skin barrier can be visualized as corneocytes representing the “bricks of a wall”, and the rich lipid matrix the “mortar”. When this system breaks down, many skin diseases such as atopic dermatitis can present themselves.

Instructions for Using EpiCeram

Apply in a thin layer to the affected skin areas 2 times per day (or as needed) and massage gently into the skin. If the skin is broken, cover EpiCeram Controlled Release Skin Barrier Emulsion with a dressing of choice.



Activating the 225g Airless Pump


To activate the 225g airless pump,
press the pump head up to 20 times.



SkinTopics Video Series #1


Abby Jacobson, PA-C discusses the basics of proper skincare therapy to patients when AD is diagnosed

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Primus Care Direct is a hassle-free, mail-order pharmacy service where patients can get their EpiCeram prescription for $20, Medicare patients included. This is the lowest possible price available and includes free home delivery. If you have insurance, you may pay even less.

In addition to patient savings and convenience, Primus Care Direct saves time for healthcare practitioners by helping to increase fill rates and eliminating call-backs for prior authorizations.

EpiCeram is also available at retail pharmacies, but Primus Care Direct guarantees patients will pay the lowest possible price on their prescription.